 The
"Expanded
Gold Standard":
Defining True,
Patient Positive Results
Because DNA amplification technology has the potential
for significantly greater sensitivity, the definition
of a true positive result now shows us that the
sensitivity of most tests is significantly lower
than originally believed.13,18
The BD BeAware™ test was developed using BD's
proprietary DNA amplification technology called Strand
Displacement Amplification (SDA). The
BD BeAware™ test is performed on the
BD ProbeTec™ ET system.
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References
13
Black CM. 1997. Current methods of laboratory diagnosis of
Chlamydia trachomatis infections. Clin. Microbiol.
Rev. 10:160-184.
18
Schacter J.,, et al. 1992. Nonculture tests for genital tract
chlamydia infection. What does the package insert mean, and
will it mean the same thing tomorrow? Sex. Transm. Dis. 19:243-244.
19 Fuller D, Davis T, Lineback P, Milish M, Jasper
L. 2000. Comparison of BDProbeTec ET, Abbott LCx, Roche Cobas
Amplicor and Gen-Probe PACE2 Assay for the detection of Chlamydia
trachomatis and Neisseria gonorrhoeae in female
urine and swab specimens. As presented at the 100th annual
meeting of the American Society for Microbiology, Anaheim,
CA.
20 Chandler L, Reisner B, English P, Fraser J,
Fulcher P, Fahlen D, Gately T, Woods G. 2000. Evaluation of
the BDProbeTec ET assay for diagnosis of Chlamydia trachomatis
and Neisseria gonorrhoea infec-tions. As presented
at the 100th annual meeting of the American Society for Microbiology,
Anaheim, CA.
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