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Bovine Albumin (Fraction V) 0.2% in 0.85% Saline, 10mL, is supplied in liquid form for use in specimen digestion procedures for the isolation of Mycobacterium species.¹ Bovine albumin is also known as bovine serum albumin or BSA.

Davis and Dubos² recommended the use of bovine albumin at a final concentration of 0.5% in liquid media for culturing Mycobacterium tuberculosis. In this study, bovine albumin neutralized the toxicity of fatty acids and permitted more luxuriant growth of M. tuberculosis.

Examine tubes for microbial contamination, evaporation, or other signs of deterioration.

Quality control requirements must be performed in accordance with applicable local, state and/or federal regulations or accreditation requirements and your laboratory's standard Quality Control procedures. It is recommended that the user refer to pertinent NCCLS guidance and CLIA regulations for appropriate Quality Control practices.

For in vitro Diagnostic Use.

Tubes with tight caps should be opened carefully to avoid injury due to breakage of glass.

Pathogenic organisms, including hepatitis viruses and Human Immunodeficiency Virus, may be present in clinical specimens. "Standard Precautions"^4-7 and institutional guidelines should be followed in handling all items contaminated with blood and other body fluids. Prior to discarding, sterilize specimen containers and other contaminated materials by autoclaving.

Biosafety Level 2 practices and procedures, containment equipment and facilities are required for non-aerosol-producing manipulations of clinical specimens such as preparation of acid-fast smears. All aerosol-generating activities must be conducted in a Class I or II biological safety cabinet. Biosafety Level 3 practices, containment equipment and facilities are required for laboratory activities in the propagation and manipulation of cultures of M. tuberculosis and M. bovis. Animal studies also require special procedures.⁶