Product Center

V-C-N Inhibitor is an antibiotic mixture of vancomycin, colistin and nystatin which is incorporated into culture media to permit selective isolation of Neisseria gonorrhoeae and N. meningitidis. V-C-N-T Inhibitor contains the same antibiotic mixture as V-C-N Inhibitor with the addition of trimethoprim to improve recovery of pathogenic Neisseria by increasing selectivity of isolation media.

Media containing V-C-N Inhibitor, e.g., Thayer-Martin Selective Agar,¹ are used for isolation of pathogenic Neisseria from the throat, vagina, rectum or urethra.^1-3 Not only is the overgrowth of gonococci and meningococci by contaminants minimized, but the "saphrophytic" Neisseria species are almost completely suppressed.

Martin et al. modified Thayer-Martin Selective Agar by adding trimethoprim to produce Transgrow Medium in bottles with a carbon dioxide-enriched atmosphere and Modified Thayer-Martin Agar in plates.^4,5 A significantly greater number of positive gonococcal isolates from clinical specimens was reported as compared with Thayer-Martin Selective Agar due to the inhibition of swarming Proteus species.^5-7 Because of its improved performance, it is recommended over earlier formulations for the isolation of N. gonorrhoeae.^8-10

Examine lyophilized and reconstituted supplement for signs of deterioration. Check performance of the finished medium by inoculation with pure cultures of stable control organisms, producing known, desired reactions. The following cultures are recommended:

Modified Thayer-Martin Agar and Transgrow Medium with Trimethoprim
In addition to the cultures listed above:

*Adjusted and/or supplemented as required to meet performance criteria.

For Laboratory Use.

V-C-N Inhibitor and V-C-N-T Inhibitor are for use in culture media and not for use in human or animal therapy. Observe aseptic techniques in the reconstitution and addition of these media supplements. Read "Instructions."

This product contains dry natural rubber.