United States
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 Neisseria Meningitidis Antiserum Group B, 1 mL |
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| Cat. # | Desc. | Qty. | Unit |
| 222291 | Neisseria Meningitidis Antiserum Group B, 1 mL | 1 | EA |
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Difco™ Neisseria Meningitidis Antisera are recommended for use in slide agglutination tests for serotyping Neisseria meningitidis.
| Catalog # | Description | Quantity | Unit |
| 222291 |
Neisseria Meningitidis Antiserum Group B, 1 mL
Contains Mercury. Dispose of Properly.
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1 | EA |
Difco™ Neisseria Meningitidis Antisera are recommended for use in slide agglutination tests for serotyping Neisseria meningitidis. Difco™ Neisseria Meningitidis Antisera are recommended for use in slide agglutination tests for serotyping Neisseria meningitidis. Neisseria meningitidis, also known as meningococcus, is found in the oropharynx and nasopharynx of humans. Because the organism survives poorly in the environment, humans are the primary reservoir. In asymptomatic persons the carrier state lasts for variable time periods, usually several weeks. The microorganism is transmitted from person-to-person by direct contact with respiratory secretions or airborne droplets.1,2 Typical human specimens for isolating the organism are: cerebrospinal fluid (CSF), blood, skin lesions (in cases where petechiae occur) and nasopharyngeal swabs. N. meningitidis occurs in the cervix and vagina of females and can cause serious pelvic disease. Other sites include the anal canal and in males, the urethra. N. meningitidis is divided into serologic groups based on the presence of either capsular or outer membrane protein antigens. Among the currently recognized groups are A, B, C, D, 29E, H, I, K, L, X, Y, Z, Z' and W135. Groups A, B, C, Y and W135 are most frequently implicated in systemic disease.3 Other serogroups are sporadically isolated from carriers and patients with disease. N. meningitidis are gram–negative cocci usually occurring in pairs called diplococci. They are strict aerobes and produce the enzyme cytochrome oxidase. The growth of N. meningitidis is enhanced by a CO2-enriched atmosphere. Neisseria meningitidis, also known as meningococcus, is found in the oropharynx and nasopharynx of humans. Because the organism survives poorly in the environment, humans are the primary reservoir. In asymptomatic persons the carrier state lasts for variable time periods, usually several weeks. The microorganism is transmitted from person-to-person by direct contact with respiratory secretions or airborne droplets.1,2 Typical human specimens for isolating the organism are: cerebrospinal fluid (CSF), blood, skin lesions (in cases where petechiae occur) and nasopharyngeal swabs. N. meningitidis occurs in the cervix and vagina of females and can cause serious pelvic disease. Other sites include the anal canal and in males, the urethra. N. meningitidis is divided into serologic groups based on the presence of either capsular or outer membrane protein antigens. Among the currently recognized groups are A, B, C, D, 29E, H, I, K, L, X, Y, Z, Z' and W135. Groups A, B, C, Y and W135 are most frequently implicated in systemic disease.3 Other serogroups are sporadically isolated from carriers and patients with disease. N. meningitidis are gram–negative cocci usually occurring in pairs called diplococci. They are strict aerobes and produce the enzyme cytochrome oxidase. The growth of N. meningitidis is enhanced by a CO2-enriched atmosphere. At the time of use, test both positive and negative control cultures to check performance of the antisera, techniques and methodology. Quality control requirements must be performed in accordance with applicable local, state and/or federal regulations or accreditation requirements and your laboratory's standard Quality Control procedures. It is recommended that the user refer to pertinent NCCLS guidance and CLIA regulations for appropriate Quality Control practices. Difco Neisseria Meningitidis Antisera are stable, lyophilized, polyclonal rabbit antisera containing approximately 0.02% thimerosal as a preservative. The Difco Neisseria Meningitidis Antisera detect the following antigenic groups:
When properly rehydrated and used as described (see Procedure) each vial of Difco Neisseria Meningitidis Antiserum is sufficient reagent for 20 slide tests. For in vitro Diagnostic Use. The Packaging of This Product Contains Dry Natural Rubber. Observe aseptic techniques and established precautions against microbiological hazards throughout all procedures. After use, specimens, containers, slides, tubes and other contaminated material must be sterilized by autoclaving. Directions for use should be followed carefully. | ||||||||||||||||||||||||||||||||||||||||||
Information shown on this page is a short summary extracted from the Package Insert, available as a PDF under the Related Documents section of this page.
