United States
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 Haemophilus Influenzae Antiserum Poly, 1 mL |
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| Cat. # | Desc. | Qty. | Unit |
| 222371 | Haemophilus Influenzae Antiserum Poly, 1 mL | 1 | EA |
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Difco™ Haemophilus Influenzae Antisera are recommended for use in slide agglutination tests for serotyping Haemophilus influenzae.
| Catalog # | Description | Quantity | Unit |
| 222371 |
Haemophilus Influenzae Antiserum Poly, 1 mL
Contains Mercury. Dispose of Properly.
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1 | EA |
Difco™ Haemophilus Influenzae Antisera are recommended for use in slide agglutination tests for serotyping Haemophilus influenzae. Difco™ Haemophilus Influenzae Antisera are recommended for use in slide agglutination tests for serotyping Haemophilus influenzae. H. influenzae constitutes part of the normal respiratory flora of humans and many animal species and can cause a variety of diseases from chronic respiratory infections to meningitis. Most of the H. influenzae isolates associated with meningitis belong to serotype b.1 H. influenzae is a nonmotile, facultative anaerobe requiring both factor X (hemin) and factor V (nicotinamide adenine dinucleotide, NAD) for in vitro growth. In microscopic morphology, the organism is a pleomorphic gram-negative coccobacillus that sometimes forms threads or filaments. The presence of a polysaccharide capsule is a major virulence factor for strains of H. influenzae that cause systemic infections. H. influenzae is divided into serologic groups a,b,c,d,e and f based on capsular polysaccharides. Most encapsulated strains that cause infection belong to serotype b.2 The encapsulated strains are referred to as “typeable strains.” Unencapsulated or “nontypeable” strains may also cause infection, but infections caused by unencapsulated strains are usually limited to the upper respiratory tract.2 Antigenic similarities exist between H. influenzae and a number of unrelated bacteria. For example, H. influenzae serotype b shares cross-reacting antigens with Streptococcus pneumoniae serotypes 6, 15a, 29 and 35a (see “LIMITATIONS OF THE PROCEDURE”). H. influenzae constitutes part of the normal respiratory flora of humans and many animal species and can cause a variety of diseases from chronic respiratory infections to meningitis. Most of the H. influenzae isolates associated with meningitis belong to serotype b.1 H. influenzae is a nonmotile, facultative anaerobe requiring both factor X (hemin) and factor V (nicotinamide adenine dinucleotide, NAD) for in vitro growth. In microscopic morphology, the organism is a pleomorphic gram-negative coccobacillus that sometimes forms threads or filaments. The presence of a polysaccharide capsule is a major virulence factor for strains of H. influenzae that cause systemic infections. H. influenzae is divided into serologic groups a,b,c,d,e and f based on capsular polysaccharides. Most encapsulated strains that cause infection belong to serotype b.2 The encapsulated strains are referred to as “typeable strains.” Unencapsulated or “nontypeable” strains may also cause infection, but infections caused by unencapsulated strains are usually limited to the upper respiratory tract.2 Antigenic similarities exist between H. influenzae and a number of unrelated bacteria. For example, H. influenzae serotype b shares cross-reacting antigens with Streptococcus pneumoniae serotypes 6, 15a, 29 and 35a (see “LIMITATIONS OF THE PROCEDURE”). At the time of use, test both positive and negative control cultures to check performance of the antisera, techniques and methodology. Difco Haemophilus Influenzae Antisera are stable, lyophilized, polyclonal rabbit antisera containing approximately 0.02% thimerosal as a preservative. When properly rehydrated and used as described (see PROCEDURE) each vial of Difco Haemophilus Influenzae Antiserum is sufficient reagent for 20 slide tests. For in vitro Diagnostic Use. The packaging of this product contains Dry Natural Rubber. Observe aseptic technique and established precautions against microbiological hazards throughout all procedures. After use, specimens, containers, slides, tubes and other contaminated material must be sterilized by autoclaving. Directions for use should be followed carefully. | |||||||||||
Information shown on this page is a short summary extracted from the Package Insert, available as a PDF under the Related Documents section of this page.
