United States
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 Salmonella Flagellar d Antigen, 5 mL |
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| Cat. # | Desc. | Qty. | Unit |
| 240785 | Salmonella Flagellar d Antigen, 5 mL | 1 | EA |
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Febrile Antigens are used in agglutination tests as an aid in the diagnosis of certain febrile diseases such as salmonellosis, brucellosis and rickettsial diseases. The patient's serum is tested directly for homologous antibodies by either a slide or tube agglutination test. These tests are qualitative and semi-quantitative. The rapid slide test is used primarily as a screening procedure especially useful when large numbers of sera must be examined. The tube test should be used to confirm positive results obtained by the slide test.
Febrile Control Antisera are used in agglutination tests in conjunction with Febrile Antigens as positive or negative controls.
| Catalog # | Description | Quantity | Unit |
| 240785 |
Salmonella Flagellar d Antigen, 5 mL
(Typhoid H)
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1 | EA |
Febrile Antigens are used in agglutination tests as an aid in the diagnosis of certain febrile diseases such as salmonellosis, brucellosis and rickettsial diseases. The patient's serum is tested directly for homologous antibodies by either a slide or tube agglutination test. These tests are qualitative and semi-quantitative. The rapid slide test is used primarily as a screening procedure especially useful when large numbers of sera must be examined. The tube test should be used to confirm positive results obtained by the slide test. Febrile Control Antisera are used in agglutination tests in conjunction with Febrile Antigens as positive or negative controls. Febrile Antigens are used in agglutination tests as an aid in the diagnosis of certain febrile diseases such as salmonellosis, brucellosis and rickettsial diseases. The patient's serum is tested directly for homologous antibodies by either a slide or tube agglutination test. These tests are qualitative and semi-quantitative. The rapid slide test is used primarily as a screening procedure especially useful when large numbers of sera must be examined. The tube test should be used to confirm positive results obtained by the slide test. Febrile Control Antisera are used in agglutination tests in conjunction with Febrile Antigens as positive or negative controls. Febrile antigen tests are serological applications of the classical Widal reaction devised for the diagnosis of typhoid fever and the Weil-Felix reactions where antigens prepared from a Proteus organism are used to detect related rickettsial antibodies.1,2 Serological diagnosis of patients suspected of having infectious diseases characterized by persistent fever is dependent upon demonstration of an agglutination reaction between the appropriate antigen and the patient's serum. The natural response to the invasion by pathogenic organisms is the production of antibodies. This immune response is highly individualized and in addition to the host's physiological status and genetic capabilities, a number of other factors are involved with the production of antibodies to a particular stimulus. These include the antigenicity of the organism, the total amount introduced to the host and the route of introduction, and whether the host has had previous exposure to the organism. These factors will determine the rate of antibody formation, the amount of antibodies produced and their persistence in the circulatory system. Febrile antigen tests are serological applications of the classical Widal reaction devised for the diagnosis of typhoid fever and the Weil-Felix reactions where antigens prepared from a Proteus organism are used to detect related rickettsial antibodies.1,2 Serological diagnosis of patients suspected of having infectious diseases characterized by persistent fever is dependent upon demonstration of an agglutination reaction between the appropriate antigen and the patient's serum. The natural response to the invasion by pathogenic organisms is the production of antibodies. This immune response is highly individualized and in addition to the host's physiological status and genetic capabilities, a number of other factors are involved with the production of antibodies to a particular stimulus. These include the antigenicity of the organism, the total amount introduced to the host and the route of introduction, and whether the host has had previous exposure to the organism. These factors will determine the rate of antibody formation, the amount of antibodies produced and their persistence in the circulatory system. At time of use, apply both positive and negative antisera controls to check performance of the antigens, techniques and methodology. The use of Francisella tularensis Antiserum (Cat. No. 240939) can aid in the control of both positive results with Francisella tularensis Antigen and cross reactions, especially with Brucella abortus Antigen. Quality control requirements must be performed in accordance with applicable local, state and/or federal regulations or accreditation requirements and your laboratory's standard Quality Control procedures. It is recommended that the user refer to pertinent NCCLS guidance and CLIA regulations for appropriate Quality Control practices. Febrile Antigen Set Contains Febrile Antigens: Salmonella O Group D (9-12) (Typhoid O)Salmonella Flagellar Group a Salmonella Flagellar Group b Salmonella Flagellar Group d (Typhoid H) Brucella abortus Proteus OX19 Control Antisera: Salmonella Somatic Polyvalent Antiserum (A, B, D)Salmonella Flagellar Polyvalent Antiserum (a, b, d) Brucella Positive Control Antiserum (AMS) Proteus Polyvalent Antiserum (OXK, OX2, OX19) Febrile Antigen Negative Control Febrile Antigens are nonviable bacterial cells in 0.5% phenolized saline with added crystal violet, brilliant green and chemical stabilizers. The Salmonella Flagellar Antigens (Cat. No. 240785, 240834, 240835) and Francisella Tularensis Antigen (Cat. No. 241050) contain 0.5% formaldehyde in place of the phenol. Febrile Control Antisera are preparations of rabbit antiserum with 30%–50% glycerin as preservative. Febrile Antigen Negative Control is Bovine Albumin (2.5%) with 50% glycerin as preservative. For in vitro Diagnostic Use. The Packaging of This Product Contains Dry Natural Rubber. Warning: May cause sensitization by skin contact. Avoid contact with skin. Wear suitable gloves. If swallowed, seek medical advice immediately and show this container or label. Pathogenic microorganisms, including hepatitis viruses and Human Immunodeficiency Virus, may be present in clinical specimens. "Standard Precautions"4-7 and institutional guidelines should be followed in handling all items contaminated with blood and other body fluids. Prior to discarding, sterilize specimen containers and other contaminated materials by autoclaving. | |||||||||||
Information shown on this page is a short summary extracted from the Package Insert, available as a PDF under the Related Documents section of this page.
