Molecular Diagnostic Solutions


BD GeneOhm™ StaphSR Assay

S. aureus is a major cause of nosocomial infections with clinical manifestations ranging from pustules to sepsis and death.1 Treatment of S. aureus infections has become a real challenge with the emergence of strains resistant to previously effective antimicrobial agents. Methicillin-resistant strains of S. aureus are frequently encountered in health-care settings, and represent nearly 60% of isolates from hospital acquired S. aureus in some North American hospitals2. Timely identification and treatment of these infections has been proven to reduce healthcare costs and improve patient outcomes. With results in less than two hours, versus 2 to 3 days with traditional culture, the BD GeneOhm™ StaphSR Assay is the first test to simultaneously detect and differentiate S. aureus (SA) and methicillin-resistant S. aureus (MRSA) direct from positive blood culture. Like the BD GeneOhm™ MRSA ACP Assay, the BD GeneOhm™ StaphSR Assay is a rapid real-time PCR test for MRSA DNA. However, the BD GeneOhm™ StaphSR test goes a step further to identify MRSA and SA DNA in clinical specimens. The test is currently available for rapid identification and differentiation of MRSA/SA in positive blood cultures to aid in the prompt and appropriate treatment of BSIs caused by these organisms.


References

  1. Centers for Disease Control and Prevention. Methicillin-resistant Staphylococcus aureus skin or soft tissue infection in a state prison. Mississippi, 2000. MMWR 2001; 50:919-922.
  2. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 to June 2004, issued October 2004. Am J Infect Control. 2004; 32:470-485.

 

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