The state of IV catheter declotting agents for clearing occluded catheters

What Shall We Do Without Urokinase?

The history of the FDA’s warnings, citations and communications with the public can be found in the following links.

Difficulties in obtaining sufficient amounts of Urokinase (Abbokinase®) – 12/11/98

http://www.fda.gov/cder/biologics/infosheets/abb121198.htm

Important Drug Warning – 1/25/99

http://www.fda.gov/cder/biologics/ltr/abb012599.htm

 

Update on Abbokinase® (Urokinase) – 3/16/99

http://www.fda.gov/cder/biologics/infosheets/abb031699.htm

 

Warning Letter to Abbott from the FDA – 3/19/99

http://www.fda.gov/cder/biologics/ltr/abb031999.pdf

 

Update on Abbokinase® (Urokinase) – 3/22/99

http://www.fda.gov/cder/biologics/infosheets/abb032299.htm

 

Abbott Communication from the FDA – 7/14/99

http://www.fda.gov/cder/biologics/ltr/abb071499.pdf

 

FDA Talk Paper – 7/16/99

http://www.fda.gov/bbs/topics/ANSWERS/ANS00964.html

Important Safety Information from AstraZeneca

http://www.fda.gov/medwatch/safety/1999/strept.htm