The importance of injection site rotation

Oct 13, 2017

There is good reason why it’s important to correctly rotate your injection sites. Lipohypertrophy, or lipo by its more common name, is a build-up of fatty lumps that occur when diabetes medication is repeatedly injected into the same site. These fatty lumps don’t absorb your medication in the same way as healthy tissue, and can lead to variable blood glucose levels and increased medication dose requirements.1,2

So not only is it important to inject your diabetes medication correctly, it's also important to be mindful of where you inject your medication. By using a new site every time, you inject, you will reduce the risk of developing lipo (fatty lumps) and will give your skin a chance to heal.2

You should never inject into damaged tissue like scars or existing lipos because it can change the way your diabetes medication is absorbed.2

Injection sites should be rotated with every injection. Inject at least one finger-width away from your previous injection site and try not to use an injection site more than once every four weeks.2

Common injection areas are:2

  • Abdomen (at least 5cm away from the belly button)
  • Thighs (upper outer part of the thighs)
  • Buttocks (upper external part of the buttocks)

To avoid developing lipo (fatty lumps) at your injection sites, be sure to:2

  • Choose a new site for every injection
  • Inject medication at least 1cm or one finger-width away from your last injection site
  • Use a new needle for every injection

Talk to your Healthcare Professional about developing an injection site rotation plan that works for you.

  1. Blanco M, Hernandez M, Strauss K, et al. Diabetes Metab. 2013; 39(5): 445-53.
  2. Frid AH, Kreugel G, Grassi G, et al. Mayo Clin Proc. 2016;91(9):1231–1255.