Published Studies

Related studies

Chlorhexidine-alcohol versus povidone-iodine for surgical-site antisepsis

  • Darouiche RO, Wall MJ, Itani KMF, Otterson MF, Webb AL, Carrick MM, Miller HJ, Awad SS, Crosby CT, Mosier MC, Alsharif A, Berger DH. N Engl J Med. 2010; 362:18-26.

Prospective, randomised clinical trial to compare the efficacy of two 70% isopropyl alcohol (IPA) solutions containing either 0.5% (v/v) or 2% (v/v) chlorhexidine gluconate (CHG) for skin-antisepsis during coronary artery bypass grafting (CABG)

  • Casey AL, Itrakjy AS, Harbun C, Clethro A, Lambert PA, Bonser RS, Graham TR, Mascaro J, Pagano D, Rooney SJ, Wilson IC, Elliot TSJ. Poster presented at European Congress of Clinical Microbiology and Infection Diseases (ECCMID), Barcelona, Spain. April 2008.

Reducing blood-culture contamination rates by the use of a 2% chlorhexidine solution applicator in acute admission units

  • Madeo M, Barlow G. J Hosp Infect 2008;69:307-9

Three Years Experience in Implementing HICPAC Recommendations for the Reduction of Central Venous Catheter–related Bloodstream Infections

  • Garcia R, Jendresky L, Landesman S, Maher A, Nicolas F. Three years experience in implementing HICPAC recommendations for the reduction of central venous catheter–related bloodstream infections. Manag Infect Control. 2003;10:42–49.

Prevention of Infections Related to Central Venous Catheters and Arterial Catheters in Intensive Care Patients

  • Kelly JW, Usry G, Blackhurst D, Bushey M, Steed C. Prevention of infections related to central venous catheters and arterial catheters in intensive care patients: a prospective randomized trial of chlorhexidine gluconate (CHG) versus povidone iodine (PI). Presented at: 15th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America; April 9–12, 2005; Los Angeles, Calif. Abstract 165.

Efficacy of Surgical Preparation Solutions in Foot and Ankle Surgery

  • Ostrander RV, Botte MJ, Brage ME. Efficacy of surgical preparation solutions in foot and ankle surgery. J Bone Joint Surg Am. 2005;87:980-985.

Cutting Surgical–site Infection Rates for Pacemakers and Implantable Cardioverter Defibrillators

  • Taylor BA. Cutting surgical–site infection rates for pacemakers and ICDs. Nursing. 2006;36:18–19.

Translating Evidence into Practice to Prevent Central Venous Catheter–associated Bloodstream Infections: A Systems–based Intervention

  • Young EM, Commiskey ML, Wilson SJ. Translating evidence into practice to prevent central venous catheter-associated bloodstream infections: a systems–based intervention. Am J Infect Control. Oct 2006;34(8):503–506

Current Approaches for the Prevention of Surgical Site Infections

  • Florman S, Nichola R L. Tulane Abdominal Transplant Institute, Tulane University School of Medicine, New Orleans, Louisiana Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana. Current Approaches for the Prevention of Surgical Site Infections. Am J Infect Dis 3 (1): 51–61, 2007

Prevention of Perioperative Infection

  • Fletcher N, D’Mitri Sofianos, Marschall Brantling Berkes and William T. Obremskey. Prevention of Perioperative Infection (Current Concepts Review). The Journal of Bone and Joint Surgery. July 2007

Evaluation of a 2% Chlorhexidine Gluconate in 70% Isopropyl Alcohol Skin Disinfectant

  • Adams D, Quayum M, Worthington T, Lambert P, Elliot T. Evaluation of a 2% chlorhexidine gluconate in 70% isopropyl alcohol skin disinfectant. J Hosp Infect. 2005;61:287–290.

Evidence Based Fact Sheet: An Effective Method for Implementing Change

  • Atherton SL, Tjoelker RC. Evidence based fact sheet: an effective method for implementing change. Am J Infect Control. 2006;34:E51.

Developing a CQI Model to Identify Best Practices in Hemodialysis Catheter Care Using a 2% Chlorhexidine (CHG) and 70% Isopropyl Alcohol (IPA) No Touch Applicator

  • Balovlenkov EK. Developing a CQI model to identify best practices in hemodialysis catheter care using a 2% chlorhexidine (CHG) and 70% isopropyl alcohol (IPA) no touch applicator [abstract]. Nephrol Nurs J. 2004; 31:139-140.

Comparison of Chlorhexidine and Tincture of Iodine for Skin Antisepsis in Preparation for Blood Sample Collection

  • Barenfanger J, Drake C, Lawhorn J, Verhulst SJ. Comparison of chlorhexidine and tincture of iodine for skin antisepsis in preparation for blood sample collection. J Clin Microbiol. 2004;42:2216–2217.

Eliminating Catheter–related Bloodstream Infection in the Intensive Care Unit

  • Berenholtz SM, Pronovost, PJ, Lipsett PA, et al. Eliminating catheter–related bloodstream infections in the intensive care unit. Crit Care Med. 2004;32:2014–2020.

Team Approach to Reducing Central Line–associated Bacteremia in Adult Intensive Care Units

  • Berriel–Cass D, Fakih M, Hopfner D. Team approach to reducing central line bacteremia in adult intensive care units. St. John Hospital and Medical Center, Detroit, Mich. Presented at: 15th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America; April 9–12, 2005; Los Angeles, Calif. Abstract No. 161.

A Patient Safety Initiative to Reduce Central Line–associated Bacteremias

  • Bevan M, Karwa M, Adams A, Currie BP. A patient safety initiative to reduce central–line associated bacteremias.Am J Infect Control. 2006;34:E76.

Prevent Nosocomial Infections at the Start

  • Carpenter D. Prevent nosocomial infections at the start. Mater Manag Health Care. 2006;15:46?48.

Reduced Catheter–related Bloodstream Infections with Alcohol Hand Rub, Chlorhexidine Patches, and Chlorhexidine/Alcohol Skin Antiseptic in 3 Intensive Care Units

  • Duncan RA, Willey S, Malone T, et al. Reduced catheter–related bloodstream infections (CRBSI) with alcohol hand rub, chlorhexidine patches and chlorhexidine/alcohol skin antiseptic in 3 ICUs. Presented at: 15th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America; April 9–12, 2005; Los Angeles, Calif. Abstract 29.

Reducing Catheter–related Bloodstream Infections: An Extended–care Facility's Process Improvement Experience

  • Earhart A, Kaminski D. Reducing catheter–related bloodstream infections: an extended–care facility's process improvement experience. JAVA. 2006;11:90–94.

Continuing Evolution of Multidisciplinary Approach to Prevention of Central Line–associated Bacteremias

  • Fauerbach LL, Ruse C, Gross MA, et al. Continuing evolution of multidisciplinary approach to prevention of central line–associated bacteremias. Am J Infect Control. 2004; 32:E40.

Antimicrobial Activity of a Recently Approved Chlorhexidine–isopropyl Alcohol Antiseptic vs. 70% Isopropyl Alcohol: A Randomized, Blinded Trial

  • Garcia R, Hibbard JS. Antimicrobial activity of a recently approved chlorhexidine-isopropyl alcohol antiseptic vs 70% isopropyl alcohol: a randomized, blinded trial. Presented at: 28th Annual Educational Conference and International Meeting of the Association for Professionals in Infection Control and Epidemiology; June 10–14, 2001; Seattle, WA. Abstract 194.

Comparison of ChloraPrep and Betadine® as Patient Preoperative Skin Preparation Antiseptics

  • Garcia R, Mulberry G, Brady A, Hibbard JS. Comparison of ChloraPrep and Betadine as preoperative skin preparation antiseptics. Poster presented at: 40th Annual Meeting of the Infectious Diseases Society of America; October 25, 2002; Chicago, Ill. Abstract 100698.

Reduction of Central Line Associated Bacteremias Using the Current Conditions Approach

  • George DJ, Grossberger S, Cannella B, Rao N. Reduction of central line associated bacteremias using the current conditions approach. UPMC Presbyterian Shadyside, Pittsburgh, Pa. Presented at: 15th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America; April 9–12, 2005; Los Angeles, Calif. Abstract 164.

Analyses Comparing the Antimicrobial Activity and Safety of Current Antiseptic Agents: a Review

  • Hibbard J. Analyses comparing the antimicrobial activity and safety of current antiseptic agents: a review. J Infus Nurs. 2005;28:194– 207.

A Clinical Study Comparing the Skin Antisepsis and Safety of ChloraPrep, 2% CHG + 70% IPA and 2% Aqueous CHG

  • Hibbard JS, Mulberry GK, Brady AR. A clinical study comparing the skin antisepsis and safety of ChloraPrep, 70% isopropyl alcohol, and 2% aqueous chlorhexidine. J Infus Nurs. 2002;25:244–249.

An Effective Intervention Program That Resulted in a Sustained Significant Reduction in Catheter-associated Bloodstream Infections in 3 Intensive Care Units

  • Koch D, Sykora C, Ferrara L, Griesbaum R, Cruz O. An effective intervention program that resulted in a sustained significant reduction in catheter–associated bloodstream infections in three intensive care units (ICUs). Am J Infect Control. 2005;33:E26.

Prevention of Intravascular Catheter–related Infections Using Chlorhexidine Gluconate Antiseptic

  • Kokales P. Prevention of intravascular catheter–related infections using chlorhexidine gluconate antiseptic. Nephrol Nurs J. 2004; 31:139-140. Abstract.

Decrease in Infectious Complications in a Pediatric Home Parenteral Nutrition Patient: Impact of Clinical Interventions

  • Kumpf VJ. Decrease in infectious complications in a pediatric home parenteral nutrition patient: impact of clinical interventions. Poster presented at: Nutrition Week; February 9–12, 2004; Las Vegas, Nev.

Long–Term Use of ChloraPrep for Skin Antisepsis in Home Parenteral Nutrition Patients

  • Kumpf VJ, Okamoto R, Diamantidis T. Long-term use of chlorhexidine for skin antisepsis in home parenteral nutrition patients. NCP. 2004; 19:73. Abstract 17.

Reduction of Central Line–associated Bloodstream Infections in a Large Healthcare System

  • Muto CA, Chang H, Solando F. Sustained Reduction of central line–associated blood–stream infections (CLABS) in a large healthcare system. Presented at: 16th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America; April 9–12, 2006; Chicago, Ill. Abstract.

Efficacy of Preoperative Antimicrobial Skin Preparation Solutions on Biofilm Bacteria.

  • Paulson DS. Efficacy of preoperative antimicrobial skin preparation solutions on biofilm bacteria. AORN J. 2005;81:492-501.

An Intervention to Decrease Catheter–related Bloodstream Infections in the ICU

  • Pronovost P, Needham D, Bernholtz S. An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med. 2006;355(26):2725–2732

Building a Culture of Patient Safety by Eliminating Central Line–associated Bloodstream Infections

  • Raimondi A, Koll B, Sayed H, Peterson K, Raucher B. Building a culture of patient safety by eliminating central line associated bloodstream infections. Am J Infect Control. 2006;34:E121–E122.

Reducing Blood Culture Contamination: What Makes the Difference?

  • Smith SM, Eng RHK, Lopez AB, Valena FD. Reducing blood culture contamination: what makes the difference? Am J Infect Control. 2006;34:E78–E79.

The Effectiveness of ChloraPrep in the Reduction of Blood Culture Contamination Rates in the Emergency Department

  • Tepus D, Cox SR, Hazelett S. The effectiveness of Chloraprep in the reduction of blood culture contamination rates in the emergency department. J Emerg Nurs. 2005;31:133. Abstract 402–C.

Skin Antisepsis Kits Containing Alcohol and Chlorhexidine Gluconate or Tincture of Iodine Are Associated With Low Rates of Blood Culture Contamination

  • Trautner BW, Clarridge JE, Darouiche RO. Skin antisepsis kits containing alcohol and chlorhexidine gluconate or tincture of iodine are associated with low rates of blood culture contamination. Infect Control Hosp Epidemiol. 2002;23:397–401.

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