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Precise WTA Reagents Provide Accurate, Simple Quantification of Genetic Information in Individual CellsJan 17, 2017
FRANKLIN LAKES, N.J., Jan. 17, 2016 - BD (Becton, Dickinson and Company) (NYSE: BDX), a leading global medical technology company, today announced the commercial availability of its new kits that provide an easier method to identify and quantify genetic information in individual cells for genomics-based research.
The process of whole transcriptome analysis (WTA) is typically used by researchers in the discovery phase to determine if an under- or over-expression of certain genes are indicative of a specific set of physical characteristics, or phenotype. Being able to quantify RNA molecules that comprise genes is a critical early stage process to determine what makes healthy cells different from diseased cells, for example, or to gain a greater understanding of the underlying causes of cell differentiation.BD Precise WTA kits include specialized reagents that can extract RNA molecules from individual cells and then "tag" each molecule with a unique molecular signature or "molecular index" to enable researchers to count each individual instance of the molecule and attribute the molecule to a specific cell. BD has over 40 years of experience analyzing proteins expressed on cell surfaces through flow cytometry, which BD has paired with Precise WTA kits to create a breakthrough offering. With this innovative combination, BD is empowering researchers to overcome the inherent limitations of current technologies and discover new connections in cell biology."The BD Precise WTA kits provide researchers with more accurate and easy-to-use genomics tools to enable more efficient identification of genetic markers for disease," said Stephen Gunstream, vice president of Genomics for BD. "The combination of our reagents, cell sorters and data analytics enables BD to support researchers from sample preparation to end data analysis."Here's how it works:
The result is a highly accurate quantification of RNA that researchers can use to investigate biological questions from diseases like cancer to stem cell development. Precise WTA is the latest addition to the BD Precise product portfolio. Researchers can use Precise WTA kits as part of the discovery phase and then use Precise Targeted kits for efficient study of a smaller set of gene targets to make the most of their research. BD Precise WTA kits are currently available for research use only and not for diagnostic or therapeutic use. For more information, contact BD at +1 650.665.2400.
BD is one of the largest global medical technology companies in the world and is advancing the world of health by improving medical discovery, diagnostics and the delivery of care. The company supports the heroes on the frontlines of healthcare by developing innovative technology, services and solutions that help advance both clinical therapy for patients and clinical process for healthcare providers. BD and its 65,000 employees have a passion and commitment to help enhance the safety and efficiency of clinicians' care delivery process, enable laboratory scientists to accurately detect disease and advance researchers' capabilities to develop the next generation of diagnostics and therapeutics. BD has a presence in virtually every country and partners with organizations around the world to address some of the most challenging global health issues. By working in close collaboration with customers, BD can help enhance outcomes, lower costs, increase efficiencies, improve safety and expand access to healthcare. In 2017, BD welcomed C. R. Bard and its products into the BD family. For more information on BD, please visit bd.com
For more information on BD, please visit bd.com.