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BD ChloraPrep™ skin preparation

Simplified, powerful and effective skin antisepsis1- 8

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BD ChloraPrep™ skin antisepsis has been demonstrated to reduce the risk of catheter-related bloodstream infections (CRBSIs)9, Surgical Site Infections (SSIs)10, and contamination of blood cultures11 and donations12 when used for the preparation of the patient’s skin prior to minor and major procedures.

BD ChloraPrep™ applicators deliver our trusted formulation including a sterile 2% w/v chlorhexidine gluconate (CHG) and 70% v/v isopropyl alcohol (IPA) through an easy-to-use design for skin prep. Applicators are available in 1 mL, 1.5 mL Frepp, 3 mL, 10.5 mL, and 26mL sizes.

We have your skin prep needs covered

5 sizes and 2 tints—The most comprehensive skin antiseptic portfolio.

Choice matters

Tailor your choice to the surface area and procedural site.

The importance of the applicator

Proprietary one-step applicator design can help you standardize practice across care settings and reduce variability.13

Simplified skin preparation

Simplify skin preparation in just one step, thanks to our easy, ready to use, single-use sterile applicators. No ancillary products are needed to complete the skin preparation process.

Skin prep you can trust

BD ChloraPrep™ may reduce the risk of catheter-related bloodstream infections (CRBSIs)9, Surgical Site Infections (SSIs)10, contamination of blood cultures11 and donations12. With more than 50 clinical publications demonstrating BD ChloraPrep™ safety and efficacy over other skin antiseptic products, it is compliant with most major national and international guidelines.14,15

A fully sterile, powerful formulation

BD ChloraPrep is the only fully sterile 2% w/v chlorhexidine gluconate (CHG) and 70% v/v isopropyl alcohol (IPA) solution in a sterile applicator, licensed and commercially available in Europe. Sterility of the solution prevents risk of intrinsic contamination16,17 increasing safety for the patient18,19.

Overall cost efficiency

BD ChloraPrep™ is an investment in skin antisepsis that may lower the overall cost of treatment and improve the quality of care by reducing the number of healthcare-associated infections (HAIs) and contamination of blood cultures and donations.³˒⁴

Product

Sterile applicators
per carton

Cartons
per case

3 year
Shelf life

DEHP or Natural Rubber Latex is
not part of the material formulation
BD ChloraPrep™ 1 mL applicator 60 4
BD ChloraPrep™ Frepp 1.5 mL applicator 20 25
BD ChloraPrep™ 3 mL applicator 25 4

BD ChloraPrep™ 10.5 mL applicator

 25 4

BD ChloraPrep™ 26 mL applicator

 25 -
References
  1. Crosby C JVAD 2001;6(1):26-31
  2. O'Donnell J Topical Antibacterials (Ch 37) in: Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 9th ed. p. 466-72, 2020
  3. McDonnell G Clin Microbiol Rev 1999;12(1):147-179
  4. Florman S Am J Infect Dis 2007;3(1):51-61
  5. Hibbard JS J Infusion Nurs 2005;28(3):194-207
  6. Garcia R Abstracts of 40th IDSA Annual Meeting 2002;Poster 418:p.117
  7. Beausoleil C J Hosp Infect 2022;129:8-16
  8. APIC 1988 Guidelines (Larsen E Am J Infect Control 1988;16(6):253-266
  9. Pronovost P, Needham D, Berenholtz S, et al. An intervention to decrease catheter-related bloodstream infections in the ICU [published correction appears in N Engl J Med. 2007 Jun 21;356(25):2660]. N Engl J Med. 006;355(26):2725-2732.
  10. Darouiche RO, Wall MJ Jr, Itani KM, et al. Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis. N Engl J Med. 2010;362(1):18-26.
  11. Madeo M, Barlow G. Reducing blood-culture contamination rates by the use of a 2% chlorhexidine solution applicator in acute admission units. J Hosp Infect. 2008;69(3):307-309.
  12. So BK, Chu CC, Ho PL, et al. Evaluation of two chlorhexidine-alcohol-based skin disinfectants in blood donation setting. Vox Sang. 2014;106(4):316-321.
  13. Casey AL, Badia JM, Higgins A, et al. Skin antisepsis: it's not only what you use, it's the way that you use it. J Hosp Infect. 2017;96(3):221-222.
  14. Centers for Disease Control and Prevention (CDC). Summary of Recommendations. https://www.cdc.gov/infectioncontrol/guidelines/bsi/recommendations.html. Accessed Aug 24, 2022.
  15. World Health Organization. WHO Surgical Site Infection Prevention Guidelines. Web Download. https://www.who.int/publications/i/item/global-guidelines-for-the-prevention-ofsurgical-site-infection-2nd-ed Accessed August 24, 2022.
  16. Degala sterile solution patent 2015. US-9078934-B1, Systems, methods, and devices for sterilizing antiseptic solutions.
  17. Swenson VA, Stacy AD, Gaylor MO, Ushijima B, Philmus B, Cozy LM, Videau NM, Videau P. Assessment and verification of commercially available pressure cookers for laboratory sterilization. PLoS One. 2018 Dec 11;13(12):e0208769.
  18. Chang C NEJM 2012; 367(23):2170-2173
  19. Bimbach D Anesth 1998;88(3):668-72
  20. Haddadin Y, Annamaraju P, Regunath H. Central Line Associated Blood Stream Infections. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan.
  21. Tepus D, Cox SR, Hazelett S. The effectiveness of Chloraprep in the reduction of blood culture contamination rates in the emergency department. J Emerg Nurs.

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