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BD ChloraPrep™ skin preparation

Simplified, powerful and effective skin antisepsis

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BD ChloraPrep™ skin antisepsis may reduce the risk of catheter-related bloodstream infections (CRBSIs) and contamination of blood cultures and donations when used for the preparation of the patient’s skin prior to minor and major procedures.

The BD ChloraPrep™ applicators deliver our trusted formulation including a sterile 2% chlorhexidine gluconate (CHG) and 70% isopropyl alcohol (IPA) through an easy-to-use design for skin prep. Applicators are available in 1 mL, 1.5 mL Frepp, 3 mL, 10.5 mL, and 26mL sizes.

Features and Benefits

We have your skin prep needs covered

5 sizes and 2 tints—The most comprehensive skin antiseptic portfolio.

Choice matters

Tailor your choice to the surface area and procedural site.

The importance of the applicator

Proprietary one-step applicator design can help you standardize practice across care settings and reduce variability. 

Simplified skin preparation

Simplify skin preparation in just one step, thanks to our easy, ready to use, single-use sterile applicators. No ancillary products are needed to complete the skin preparation process.

Skin prep you can trust

BD ChloraPrep™ may reduce the risk of catheter-related bloodstream infections (CRBSIs) and contamination of blood cultures and donations. With more than 50 clinical publications demonstrating BD ChloraPrep™ safety and efficacy over other skin antiseptic products, it is compliant with most major national and international guidelines.¹˒²

A fully sterile, powerful formulation

BD ChloraPrep™ is the only fully sterile 2% chlorhexidine gluconate (CHG) and 70% isopropyl alcohol (IPA) solution in a sterile applicator, licensed and commercially available in Europe. Sterility of the solution prevents risk of intrinsic contamination, increasing safety for the patient.

Overall cost efficiency

BD ChloraPrep™ is an investment in skin antisepsis that may lower the overall cost of treatment and improve the quality of care by reducing the number of healthcare-associated infections (HAIs) and contamination of blood cultures and donations.³˒⁴

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Please note, not all products, services or features of products and services may be available in your local area. Please check with your local BD representative.


  1. Centers for Disease Control and Prevention (CDC). Summary of Recommendations. Accessed Aug 24, 2022.
  2. World Health Organization. WHO Surgical Site Infection Prevention Guidelines. Web Download. Accessed August 24, 2022.
  3. Haddadin Y, Annamaraju P, Regunath H. Central Line Associated Blood Stream Infections. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan.
  4. Tepus D, Cox SR, Hazelett S. The effectiveness of Chloraprep in the reduction of blood culture contamination rates in the emergency department. J Emerg Nurs. 2005;31:133. Abstract 402–C.