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Sepsis

The complete implementation of a sepsis bundle can help lower the risk of mortality associated with sepsis by 31%6

In an ideal world, all sepsis cases in your institution would be diagnosed rapidly and accurately in order to enable the best treatment management decision.

But in the current state 37% is the mean mortality rate of sepsis in ICUs1

2/3

15% of patients in ICUs have severe sepsis, 2/3 are septic shocks2

7.6% per hour

Sepsis mortality increases by 7.6% per hour3

£1.1 billion

The total direct hospital costs are estimated to be up to £1.1 billion in the UK4

Beyond the high morbidity and cost, sepsis impacts the hospitals' reputation and lead to litigation. The challenges to managing sepsis lie the implemetation clinical practice–based measures (evidence-based practice interventions)5 and in timely initiation of appropriate targeted antibiotherapy.

The complete implementation of a sepsis bundle can help lower the risk of mortality associated with sepsis by 31%6

 

How BD supports you

BD supports you in sepsis diagnosis and treatment management overview

Sample quality

BD supports best practice for sample collection and blood culture, resulting in improved sample quality and greater diagnostics accuracy with a portfolio of solutions which include innovative technologies and services.

Diagnostic accuracy and timeliness

BD supports more rapid, accurate and appropriate diagnostic identification enabling effective clinical decision-making with a portfolio of solutions which include innovative technologies and services.

Surveillance and reporting

BD supports you in enabling remote multi-site diagnostic result availability with digital infrastructure for faster decision-making with a porfolio of solutions which include innovative technologies and services.

BD supports change management and continuous quality improvement

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Antimicrobial resistance

An integrated stewardship model with a holistic approach based on antimicrobial, infection prevention and diagnostic can help fight antimicrobial resistance.

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Healthcare-associated infections

Increased compliance to guidelines and standardized practices help decrease HAIs.

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Medication errors

Standardisation processes, full traceability, automation and closed-loop mediaction management can help prevent medication errors.

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*This content is intended for healthcare professionals only.
**Not all products, services or features of products and services may be available in your local area. Please check with your local BD representative.

References
  1. Vincent J-L, Jones G, David S, Olariu E, Cadwell KK. Frequency and mortality of septic shock in Europe and North America: a systematic review and meta-analysis. Crit Care Lond Engl. 2019;23(1):196. doi:10.1186/s13054-019-2478-6
  2. Brun-Buisson C. Mise au point - Épidémiologie des états septiques graves. Presse Médicale. 2006;35(3-C2):513-520. https://www.em-consulte.com/en/article/102977. Accessed March 12, 2020.
  3. Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006; 34:1589–1596.
  4. Frontier Economics. Exploring the costs of unsafe care in the NHS - A report prepared for the department of health. October 2014.
  5. Rhodes, 2017, Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016
  6. Prasad P, Shea E, Shiboski S et al. Relationship Between a Sepsis Intervention Bundle and In-Hospital Mortality Among Hospitalized Patients: A Retrospective Analysis of Real-World Data. 2017. Anesth Analg. 2017 Aug;125(2):507-513.
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