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Gastrointestinal Infections Portfolio
Targeted molecular stool testing that decreases turnaround time, increases accuracy and aids in patient management
- Overview
It can be difficult to differentiate the cause of gastrointestinal illness. Targeted testing allows clinicians to accurately decide which tests are needed according to the patient’s clinical presentation and history.
The BD MAX™ Enteric Panels provide rapid and improved detection (vs traditional methods) of bacterial, viral and parasite pathogens causing ≥ 95% of infectious diarrhoea. The comprehensive menu of enteric panels significantly reduces time, materials and labour on the stool bench within the Microbiology laboratory.
More timely and accurate results enable:
- Optimal patient management and faster results reporting to inform clinical decisions
- Improved clinical interventions, i.e. optimal antimicrobial usage and ability to bring in infection control measures earlier to prevent infection spread
HOW TARGETED TESTING CAN HELP YOU WITH GI DIAGNOSTIC CHALLENGES AND PATIENT MANAGEMENT
Infectious diarrhoea affects billions of people globally each year
~1.7 billion cases of infectious gastroenteritis diarrhoea each year1
Infectious diarrhoea is the 2nd leading cause of the death in children under 5 years of age1
Norovirus resulted in a total of $4.2 billion in direct health system costs2
The limitations of traditional methods (including culture, microscopy and immunoassay) include:
Delayed results3
Difficulty growing certain organisms on culture media4
False negative results due to subjective interpretation of microscopy5
Poor sensitivity and limited detection of targets with immunoassays6
Determining a specific clinical diagnosis can benefit a patient with infectious diarrhea by:
Directing appropriate therapy
Allowing the judicious use of antimicrobial agents
Improving patient satisfaction and life planning
BD MAX™ Enteric Bacterial Panel
Salmonella spp.
Campylobacter spp. (C. jejuni and C. coli)
Shigella spp and EIEC
Shiga toxin (stx1/stx2) genes (found in STEC)
BD MAX™ Extended Enteric Bacterial Panel
Plesiomonas shigelloides
Vibrio spp. (V. vulnuficus, V. parahaemo lyticus, V. cholerae)
Enterotoxigenic E. coli (ETEC)
Yersinia entercolitica
BD MAX™ Enteric Parasite Panel
Giardia lamblia
Cryptosporidium spp (C. hominis and C. parvum)
Entamoeba histolytica
BD MAX™ Enteric Viral Panel
Norovirus GI & GII
Rotavirus A
Adenovirus F40/41
Sapovirus (genogroups I, II, IV, V)
Human Astrovirus (hAstro
BD MAX™ Enteric Viral Panel-NR
Norovirus GI & GII
Rotavirus A
EIEC, Enteroinvasive Escherichia coli; ETEC, Enterotoxigenic Escherichia coli; hAstro, Human Astrovirus; STEC, Shiga toxin–producing Escherichia coli.
Shigella dysenteriae can possess a Shiga toxin gene identical to the Shiga toxin 1 found in STEC.
BD, the BD Logo, BD MAX™ are trademarks of Becton, Dickinson and Company or its affiliates. © 2021 BD. All rights reserved.
The BD MAX™ System, BD MAX™ Enteric Bacterial & Extended Enteric Bacterial Panels, BD MAX™ Enteric Viral Panel & BD MAX™ Enteric Viral Panel-NR, BD MAX™ Enteric Parasite Panel, BD MAX™ Vaginal Panel, BD MAX™ Check-Points CPO, BD MAX™ MRSA XT & BD MAX™ StaphSR, BD MAX™ Cdiff, BD MAX™ MDR-TB, BD SARS-CoV-2 Reagents for BD MAX™ System, BD SARS-CoV-2/Flu for BD MAX™ System, VIASURE SARS-CoV-2 (N1+N2) Real Time PCR Detection Kit for BD MAX™ System, VIASURE SARS-CoV-2, Flu (A+B) & RSV Real Time PCR Detection Kit for BD MAX™ System, VIASURE Flu A, Flu B & RSV Real Time PCR Detection Kit for BD MAX™ System, VIASURE Vancomycin Resistance Real Time PCR Detection Kit for BD MAX™ System are in vitro diagnostic medical devices bearing a CE mark.
The BD CTGC2 and BD CTGCTV2 assays for BD MAX™ System are in vitro diagnostic medical devices bearing a CE mark and are CE certified by BSI Group The Netherlands B.V. (Notified Body Number = 2797).
- World Health Organization. Diarrhoeal disease. Available at: https://www.who.int/news-room/fact-sheets/detail/diarrhoeal-disease. Accessed May 2020.
- Bartsch et al. PLoS ONE. 2016;11(4):e0151219.
- Mortensen et al. BMC Clin Pathol. 2015;15:9.
- Anderson et al. J Clin Microbiol. 2014;52(4):1222-1224.
- Centers for Disease Control and Prevention. Parasites – Amebiasis – Entamoeba histolytica Infection. Available at: https://www.cdc.gov/parasites/amebiasis/index.html. Updated December 16, 2015. Accessed May 2020.
- Humphries R et al. Clin Microbiol Rev. 2015;28(1):3-31.
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