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Customer Care

Avitene™ Ultrafoam™ Collagen Sponge

Ultrafoam™ Collagen Sponge

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Standardise on the proven solution for active hemostasis.

Avitene™ Microfibrillar Collagen Hemostat is an active absorbable collagen hemostat, proven to accelerate clot formation. Avitene™ effectively enhances platelet aggregation and the release of proteins to form fibrin, resulting in hemostasis.

Features and Benefits


  • The proven solution for controlling bleeding in all surgical applications, including neurosurgery, neurology, urology, cardiovascular and general surgery1
  • Trusted by surgeons for its safety and efficacy for over 40 years.



Avitene™ Sheets (Nonwoven web)

  • Avitene™ Sheets provide the same efficacy expected from Avitene™ Flour
  • Cut to any shape or size
  • Clings tenaciously to hemorrhage
  • Ideal for use on flat surfaces or to wrap vessels and anastomosis sites
  • Available in 3.5 cm x 3.5 cm, 7.0 cm x 3.5 cm and 7.0 cm x 7.0 cm

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Avitene™ Microfibrillar Collagen Hemostat Flour

    • Effective in controlling arterial bleeding1
    • Conforms and adheres to irregular spaces
    • Easy removal with irrigation and suction
    • Available in 0.5 g, 1.0 g and 5.0 g sizes


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    Avitene™ Ultrafoam™ Collagen Sponge

    • Easy, effective solution for hemostasis 
    • In an animal study, UltraFoam™ Collagen without thrombin was as effective as Gelfoam® Sponge with thrombin 
    • Reduced thrombin usage may lower cost 
    • Soft, pliable sponge is ready-to-use out of the package 
    • No soaking necessary
    • Does not swell, providing predictable placement of Ultrafoam™

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    1. See full Instructions for Use for detailed application instructions


    • Not all products, services, claims or features of products may be available or valid in your local area. Please check with your local BD representative.

    • Please consult product labels and instructions for use for indications, contradictions, hazards, warnings, and precautions.


    Avitene™ Ultrafoam™ sponge is indicated in surgical procedures as an adjunct to hemostasis when control of bleeding by ligature or conventional procedures is ineffective or impractical.


    • Avitene™ Ultrafoam™ sponge should not be used in the closure of skin incisions as it may interfere with the healing of the skin edges. This is due to simple mechanical interposition of dry collagen and not due to any intrinsic interference with wound healing.

    • It has been reported with other collagen hemostatic agents, that by filling porosities of cancellous bone, they may significantly reduce the bond strength of methylmethacrylate adhesives. Avitene™ Ultrafoam™ sponge should not, therefore, be employed on bone surfaces to which prosthetic materials are to be attached with methylmethacrylate adhesives.


    • Avitene™ Ultrafoam™ sponge is inactivated by autoclaving.

    • Ethylene oxide reacts with bound hydrochloric acid to form ethylene chlorohydrin.

    • This device has been designed for single use only. Reuse, reprocessing, resterilization or repackaging may compromise the structural integrity and/or essential material and design characteristics that are critical to the overall performance of the device and may lead to device failure which may result in injury to the patient. Reuse, reprocessing, resterilization or repackaging may also create a risk of contamination of the device and/or cause patient infection or cross infection, including, but not limited to, the transmission of infectious diseases from one patient to another. Contamination of the device may lead to injury, illness or death of the patient or end user. Opened, unused product should be discarded.

    • As with any foreign substance, use of Avitene™ Ultrafoam™ sponge in contaminated wounds may enhance infection.

    • Avitene™ Ultrafoam™ sponge should not be used in instances of pumping arterial hemorrhage.

    • It should not be used where blood or other fluids have pooled, or in cases where the point of hemorrhage is submerged as it may mask an underlying source of bleeding, resulting in hematoma.

    • Avitene™ Ultrafoam™ sponge will not act as a tampon or plug in a bleeding site, nor will it close off an area of blood collecting behind a tampon.

    • Avitene™ Ultrafoam™ sponge is not intended to treat systemic coagulation disorders.

    • Not for injection, intraocular or intravascular use.

    Adverse Reactions

    • The most serious adverse reactions reported, which may be related to the use of other collagen products, are potentiation of infection including abscess formation, hematoma, wound dehiscence and mediastinitis.

    • Other reported adverse reactions possibly related are adhesion formation, allergic reaction, foreign body reaction and subgaleal seroma (report of a single case), and increased incidence of alveolalgia when used for packing of dental extraction sockets.



    BD-52028 (08/22)