BD™ Bruker MALDI Biotyper® CA System

Reliable, comprehensive, and accurate identification results directly from positive blood culture or colony.

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Overview

The BD™ Bruker MALDI Biotyper® CA System* identifies microorganisms

using MALDI-TOF (Matrix-Assisted Laser Desorption/Ionization Time-of-Flight) mass spectrometry to measure a unique proteomic fingerprint of an organism.

BD™ Bruker MALDI Biotyper® CA System

The BD™ Bruker MALDI Biotyper® CA System workflow has been designed to be efficient and easy. The fully traceable workflow has been streamlined and requires only a few simple steps to generate high quality microorganism identifications.

Typically, no more than an isolated single colony from a culture is required. The entire process needs only a few minutes to complete.

The dedicated BD™ Bruker MALDI Biotyper® CA System software automates the process of acquiring the mass spectrum and performing the match against the extensive FDA-cleared reference library to provide a result. 

Features and Benefits

Comprehensive coverage

Intentional focus on library expansion which currently offers US-IVD identification for over 480 different FDA cleared species including gram-negative bacteria, gram-positive bacteria, and yeasts

Workflow optimization

Optional accessories and software modules that support sample types derived from colony or direct from positive blood culture with the MBT Sepsityper® workflow

Efficient testing

Sample focused workflow as QC spot requirements allow for test volume flexibility and the MALDI biotarget plates can be reused if not all target positions have been consumed

QC support

Bacterial Test Standards (BTS) are packaged quality controls which have been specifically designed for use with the MALDI Biotyper® and cover the entire mass range of proteins used for precise identification

Informatics supported

MALDI plate mapping supported by BD Epicenter™ with connectivity and automatic transfer of results available to BD Phoenix™ M50

Robust identification

Fast identification within minutes and high accuracy comparable to 16S rRNA gene sequencing1,2,3

Laboratory designed

Compact system with low-noise and weight (<166 lbs.) that requires less than 3 feet of counter space

Quality components

Proprietary lifetime** smartbeam™ laser and high-performance vacuum system that help generate fast target exchange times

Simple results interpretation

The result for each sample is clearly listed within the user interface and interpreted with the resulting confidence score and ‘traffic light’ color scheme

Resourceful biotarget plates

Effectively designed target plates that can support up to 96 sample positions and may help laboratories to save on time and costs through MALDI-TOF identification2,4,5

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Reference
References
  1. Burckhardt I and Zimmermann S. Susceptibility Testing of Bacteria Using MALDI-TOF Mass Spectrometry. Frontiers in Microbiology. 2018.
  2. Cherkaoui et al. Comparison of Two Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Methods with Conventional Phenotypic Identification for Routine Identification of Bacteria to the Species Level. Journal of Clinical Microbiology. 2010.
  3. Patel R. MALDI-TOF MS for the Diagnosis of Infectious Diseases. Clinical Chemistry. 2015.
  4. Bizzini A and Greub G. Matrix-assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry, A Revolution in Clinical Microbial Identification. Clinical Microbiology and Infection. 2010.
  5. Seng et al. Ongoing Revolution in Bacteriology: Routine Identification of Bacteria by Matrix-assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry. Clinical Infectious Diseases. 2009.
Notes:

* MALDI Biotyper CA System can only be sold in the US and Puerto Rico.

The MALDI Biotyper is also available in Research Use Only (RUO), General Purpose (GP) and IVD CE labels. Please contact your local representative for availability in your country.

** Lifetime means: 500 million laser shots or seven years (whichever occurs first)

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