Sepsis Management

Helping set patients at risk for sepsis on the right clinical path

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The BD Path for Sepsis Management

When it comes to patients at risk for sepsis, time to appropriate therapy is critical

By reducing time from recognition to accurate identification and treatment, you are setting them on the right clinical path. Our sepsis management program can help.

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Approach

Let’s collaborate to optimize how you manage patients across the sepsis care pathway using BD solutions. The approach will include:

  1. Aligning metrics to your initiatives
  2. Establishing a baseline with an assessment
  3. Identifying areas of improvement across people, processes and technologies
  4. Sustaining best practices through hospital champions, performance dashboards and ongoing education and training of BD solutions
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Goals

By focusing on the sepsis care pathway—from recognition of patients at-risk for sepsis through their treatment—using BD solutions, you can start on the journey of:

  • Reducing time to recognition of patients at risk for sepsis
  • Improving blood culture collection and optimizing diagnostic accuracy
  • Reducing time to detection and lab turnaround time

With the ultimate goal of reducing time to appropriate therapy and improving patient outcomes.

Sepsis Care Approach

BD® Sepsis Management Program—from initial recognition to treatment

Recognize

Mortality from septic shock increases 7.6% for every hour that treatment is delayed4 among patients with septic shock within the first 6 hours of onset of hypotension. The timely identification of a patient at risk for sepsis is necessary for setting the course of action to intervene with appropriate diagnosis and treatment.

BD HealthSight™ Clinical Advisor and Infection Advisor

Prep

~ 80% of skin flora reside in the first five layers of our outermost skin.Proper skin preparation kills bacteria on the skin that can potentially cause skin infection and contamination.

BD ChloraPrep™

Collect

~ 20% of blood culture samples have been reported as underfilled in the U.S.Support optimal blood culture specimen collection; sufficient blood volume is a critical determinant for optimal organism recovery. The yield of pathogens recovered increases in direct proportion to the volume of blood cultured. 6

BD Vacutainer® UltraTouch™ Push Button Blood Collection Set

Analyze

80% of sepsis deaths could be prevented by quicker diagnosis and treatment.Decrease time to detection, followed by timely and accurate organism identification (ID) and antimicrobial susceptibility testing (AST). Reduction in transport time and faster incubation of blood cultures has been shown to reduce turnaround times and accelerate antibiotic switching.8

BD BACTEC™ Blood Culture Media

BD BACTEC™ FX Blood Culture System

BD Kiestra™ Lab Automation System

BD Phoenix™ Automated Identification and Susceptibility Testing System

BD Synapsys™ Microbiology Informatics Solution

 

 

Treat

5x reduction in survival when inappropriate initial antimicrobial therapy is performed for septic shock, which occurs in ~20% of patients. 9  Ensuring that appropriate diagnostics are performed as early as possible to enable timely and appropriate antimicrobial therapy treatment decisions.

BD HealthSight™ Clinical Advisor

BD Phoenix™ Automated Identification and Susceptibility Testing

Medication management solutions

 

 

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Proud to support efforts in sepsis awareness and care

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References
  1. Sepsis takes more lives than opioid overdoses, but most adults don’t know. September 3, 2019. Accessed August 21, 2020. https://www.sepsis.org/news/2019-sepsis-awareness-survey/.
  2. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study [published correction appears in Lancet. 2020 Mar 28;395(10229):1038] [published correction appears in Lancet. 2020 Mar 28;395(10229):1038]. Lancet. 2020;395(10229):1054-1062. doi:10.1016/S0140-6736(20)30566-3.
  3. Data & Reports. Centers for Disease Control and Prevention. 2020. Accessed August 21, 2020. https://www.cdc.gov/sepsis/datareports/index.html
  4. Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006;34(6):1589-1596.
  5. Brown E, Wenzel RP, Hendley JO. Exploration of the microbial anatomy of normal human skin by using plasmid profiles of coagulase-negative staphylococci: search for the reservoir of resident skin flora. J Infect Dis. 1989;160(4):644-650.
  6. Lamy B, Dargère S, Arendrup MC, Parienti J-J, Tattevin P. How to optimize the use of blood cultures for the diagnosis of bloodstream infections? A state-of-the art. Front Microbiol. 2016;7:697.
  7. Sepsis Alliance. Sepsis fact sheet, 2018. Accessed August 21, 2020.
  8. Kerremans JJ, van der Bij AK, Goessens W, Verbrugh HA, Vos MC. Immediate incubation of blood cultures outside routine laboratory hours of operation accelerates antibiotic switching. J Clin Microbiol. 2009;47(11):3520-3523.
  9. Kumar A, Ellis P, Aribi Y, et al. Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock. Chest. 2009;136(5):1237-1248.

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    BD Phoenix™ automated identification and susceptibility testing system 

    The BD Phoenix system has demonstrated performance in detecting both existing and emerging resistance.

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    BD Synapsys™ Informatics Solution

    Microbiology laboratories play a key role in infectious disease management. At the same time, they face a growing list of challenges, including lab consolidation, increased regulations, decreasing reimbursements and a shortage of skilled staff. That task is complicated by inherent obstacles such as manual processes, the lack of integrated workflows, disparate IT systems and difficulties accessing data.

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    Medication management solutions

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References
  1. Sepsis takes more lives than opioid overdoses, but most adults don’t know. September 3, 2019. Accessed August 21, 2020. https://www.sepsis.org/news/2019-sepsis-awareness-survey/.
  2. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study [published correction appears in Lancet. 2020 Mar 28;395(10229):1038] [published correction appears in Lancet. 2020 Mar 28;395(10229):1038]. Lancet. 2020;395(10229):1054-1062. doi:10.1016/S0140-6736(20)30566-3.
  3. Data & Reports. Centers for Disease Control and Prevention. 2020. Accessed August 21, 2020. https://www.cdc.gov/sepsis/datareports/index.html
  4. Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006;34(6):1589-1596.
  5. Brown E, Wenzel RP, Hendley JO. Exploration of the microbial anatomy of normal human skin by using plasmid profiles of coagulase-negative staphylococci: search for the reservoir of resident skin flora. J Infect Dis. 1989;160(4):644-650.
  6. Lamy B, Dargère S, Arendrup MC, Parienti J-J, Tattevin P. How to optimize the use of blood cultures for the diagnosis of bloodstream infections? A state-of-the art. Front Microbiol. 2016;7:697.
  7. Sepsis Alliance. Sepsis fact sheet, 2018. Accessed August 21, 2020.
  8. Kerremans JJ, van der Bij AK, Goessens W, Verbrugh HA, Vos MC. Immediate incubation of blood cultures outside routine laboratory hours of operation accelerates antibiotic switching. J Clin Microbiol. 2009;47(11):3520-3523.
  9. Kumar A, Ellis P, Aribi Y, et al. Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock. Chest. 2009;136(5):1237-1248.

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