Thymine and thymidine levels are monitored and kept low during the production of BD BBL™ Mueller Hinton II Agar. This practice assures that sulfonamide and trimethoprim activity will not be inhibited. Calcium and magnesium levels are also controlled through careful screening of raw materials. Correct zone diameters are, therefore, achieved with BD BBL™ Sensi-Disc™ test discs containing aminoglycosides.
The addition of 5% sheep blood to Mueller Hinton Agar base produces a CLSI-recommended medium for testing the antimicrobial susceptibility of Streptococcus pneumoniae.