BD Neopak™ Glass Prefillable Syringe (PFS) platform and Integrated Drug Delivery

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Overview

The BD Neopak™ Glass Prefillable Syringe platform with tailorable medication delivery solution can help support the development of your biologic drug.

Getting your drug to market with a solution focused on patient safety and usability

Since 2010, we have conducted more than 80 human factor studies2 to ensure the usability of our products. Our diverse portfolio features devices and systems that can deliver biologics across a wide range of volumes and viscosities, helping to treat patients with chronic conditions.

Features and Benefits

Various configurations

  • Available in 1ml and 2.25 ml configurations
  • Designed to enhance patient experience when administering high viscosity/high volume drugs 3,4
  • Shorter 8mm needle
  • Thinner wall cannula technology

Positive patient acceptance

  • May help reduce the risk of intramuscular injection3
  • Decreased injection force and/or time at a fixed solution viscosity4
  • Reduced needle related anxiety3
  • Positive impact on patient acceptance3

Enhanced particle reduction with immobilized silicone coating

  • Designed to stabilise the silicone lubricant layer without introducing new chemistry5,6*
  • Enhanced particle reduction with immobilised silicone coating

Compatibility with sensitive biopharmaceuticals

  • Minimizing sub-visible particle generation to help meet compliance standards for particulates5,6,7
  • Stabilised silicone lubricant layer and mechanical properties to aid in full drug
  • delivery5,6,7,8
  • Maintained gliding and activation performance over time, as compared to
  • conventional silicone6

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Footnotes

*XSi does not introduce new chemical substances or molecule entity and only modifies the distribution of chemical functions which already exists in PDMS (Polydimethylsiloxane) silicone

** USP 788 standard

References

  1. World Preview 2018, Outlook to 2024. Evaluate Pharma, 2018
  2. BD-PS list of human factor studies, BD, 2020
  3. User experience for manual injection of 2 mL viscous solutions is enhanced by a new prefillable syringe with a stacked 8 mm ultra-thin wall needle, Expert Opinion on Drug Delivery, Pager 2020
  4. Injection time and ejection force calculation, BD internal study, 2020
  5. Depazet al. Cross-Linked Silicone Coating: A Novel Prefilled Syringe Technology That Reduces Subvisible Particles and Maintains Compatibility with Biologics. JOURNAL OF PHARMACEUTICAL SCIENCES 103:1384–1393, 2014
  6. BD Neopak™ XSi™ 1mlL-Competitive Benchmark [Internal Study]. Pont-de-Claix, FR: Becton Dickinson and Company; 2020
  7. BD Neopak™ XSi™ 2.25ml 27G STW ½’’ - Empty AGF. [internal Study].Pont-de-Claix, FR: Becton Dickinson and Company. 2019
  8. BD Neopak™ XSi™ 2.25ml 27G STW ½’’ - injection time. [internal Study]. Pont-de-Claix, FR: Becton Dickinson and Company. 2019
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