Accelerate Arc™ System
Automated cleanup of positive blood cultures from BD BACTEC™ bottles for microbial identification with BD MALDI Biotyper® CA System and MBT-CA Sepsityper® software extension1
The Accelerate Arc™ System is designed to help clinicians expedite antimicrobial therapy decisions by providing automated rapid cleanup of positive blood cultures for direct ID by BD MALDI Biotyper® CA System in approximately 90 minutes.2
80% of septic shock patients can be saved when appropriate antibiotic therapy is started within the first hour following onset of hypotension3
Delayed or inappropriate initial antimicrobial therapy for bloodstream infections results in prolonged hospital stays and increased mortality rates, while contributing to the silent pandemic of antimicrobial resistance.4-6
Healthcare institutions need rapid diagnostic instruments, including fast phenotypic platforms that facilitate earlier initiation of optimal therapy, to support their antimicrobial stewardship efforts and improve patient outcomes.7-10
MALDI prep, simplified
The Accelerate Arc™ System provides an automated rapid clean-up of positive blood cultures from a BD BACTEC™ bottle for direct ID by BD MALDI Biotyper® in ~90 minutes.2
Just 2-3 minutes of hands-on time is all it takes for an Accelerate Arc module and BC kit. Simple enough to run on all shifts by any technician in the lab.2
Your total cost to rapidly identify organisms from positive blood cultures could be at least 50% less than what you are paying for a rapid molecular ID solution.11-14
Complementary solutions for your identification and antimicrobial susceptibility testing needs
The BD Bloodstream Infection Solution allows you to obtain complementary identification and antimicrobial susceptibility testing results that cover many of the microbiological needs of infectious disease specialists:
- Ensure rapid and robust pathogen identification with the BD™ Bruker MALDI Biotyper® System.15-17
- Detect known and emerging antimicrobial resistance using the comprehensive panel format of the BD Phoenix™ M50.18-19
- Leverage the speed of the Accelerate Pheno® system to provide fast, actionable phenotypic susceptibility results earlier to clinicians for critical specimens.20-21
Antimicrobial stewardship programs, combined with rapid diagnostics, are critical to optimize the use of antibiotics, effectively treat infections, protect patients from harm caused by unnecessary antibiotic use, reduce the risk of developing antibiotic resistance and reduce hospital costs and length of stay.4-6,8-10,21
Already have a rapid molecular solution for positive blood culture identification? The Accelerate Arc System™ allows you to:
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Expand ID menu
Use of Arc + MALDI for positive blood culture ID workflow expands your library breadth by more than 20 times over your syndromic MDx test.23-25
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Lower your cost for rapid blood culture ID
Your total cost to rapidly ID organisms from positive blood cultures could be at least 50% less than what you are paying for rapid molecular solution.11-14
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Minimize waste
For some labs, roughly 30% of rapid molecular tests turn up as contaminants. A direct MALDI ID could allow for more selective workflows with fewer wasted kits.26
Complementary ID/AST solutions for fast, actionable identification and susceptibility results
Bloodstream Infection
Magnolia Medical Technologies
Accelerate Diagnostics
*By clicking this link you are leaving bd.com and going to a third party website. Steripath® is a registered trademark of Magnolia Medical Technologies. Pheno® is a registered trademark of Accelerate Diagnostics.
- Accelerate Arc™ Module Use Guide, (LBL000773 Rev. 2)
- Accelerate Arc™ BC Kit Instructions for Use, (LBL000774 Rev. 1)
- Kumar A et al. Crit Care Med. 2006;34(6):1589–96
- Battle SE et al. J Antimicrob Chemother. 2017;72(1):299–304.
- Burnham J et al. Open Forum Infect Dis. 2017 Oct 4;4(Suppl 1):S623–4.
- Bauer KA et al. Open Forum Infect Dis. 2022;9(11):ofac537.
- Bhalodi AA et al. Clin Infect Dis. 2022;75(2):269–77.
- Mohayya SM et al. Antimicrob Steward Healthc Epidemiol. 2023;3(1):e22.
- Sheth S et al. Antimicrob Agents Chemother. 2020;64(9):e00578–20.
- Walsh TL et al. Infection. 2021;49(3):511–9.
- Pardo et al. ASM 2014
- Doern et al. Clinical Microbiology Review 2019
- https://www.gsaadvantage.gov/ref_text/V797D30085/0XCQE4.3T33AP_V797D-30085_BIOFIREVATSCSJULY.PDF
- Accelerate Arc™ Module, MKT000289_A(1672) axdx.com
- BD™ Bruker MALDI Biotyper CA System User Manual (8603291).
- Saffert RT et al. J Clin Microbiol. 2011;49(3):887–92.
- Knabl L et al. Lett Appl Microbiol. 2021;73(1):2–8.
- BD Phoenix™ M50 Automated Microbiology System User's Manual (500008930).
- Carey RB et al. Failure of Automated Systems to Detect Vancomycin-Resistant Staphylococcus aureus. Abstract presented at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Washington, DC, 2004.
- Accelerate PhenoTest® BC kit Instructions for Use (LBL000607).
- Bhalodi AA et al. Clin Infect Dis. 2022;75(2):269–77.
- Biotyper CA (2022) library, CE-IVD: 4194 organisms
- https://www.bruker.com/en/products-and-solutions/microbiology-and-diagnostics/microbial-identification-for-clinical-laboratories-ivd-ce/maldi-biotyper-library-ivd.html
- FilmArray BCID 2 panel: 33 targets; https://www.biofiredx.com/products/the-filmarray-panels/filmarraybcid/
- Genmark BCID panels (3): ~50 targets; https://www.genmarkdx.com/panels/eplex-panels/bcid-panels/
- Doern GV, Carroll KC, Diekema DJ, Garey KW, Rupp ME, Weinstein MP, Sexton DJ. 2019. A comprehensive update on the problem of blood culture contamination and a discussion of methods for addressing the problem. Clin Microbiol Rev 33:e00009-19. https://doi.org/10.1128/CMR.00009-19