BD Neopak™ XtraFlow™ Glass Prefillable Syringe

BD solutions for enabling delivery of complex biologics

Artwork BD Neopak™ XtraFlow™ 2.25 mL Glass Prefillable Syringe With 8 mm UTW Needle & FluroTec® Stopper & Stelmi RNS 2
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Overview

The BD Neopak™ XtraFlow™ Glass Prefillable Syringe solution leverages 8mm needle length in combination with thin wall cannula to reduce pressure drop and enhance flow.1  

BD Neopak™ XtraFlow™ 1 mIL Glass Prefillable Syringe With 8 mm UTW Needle & BD SCF™ PremiumCoat® Stopper & Stelmi RNS 4
  • BD Neopak™ XtraFlow™ 1 mIL Glass Prefillable Syringe With 8 mm UTW Needle & BD SCF™ PremiumCoat® Stopper & Stelmi RNS 4
  • BD Neopak™ XtraFlow™ 2.25 mL Glass Prefillable Syringe With 8 mm UTW Needle & FluroTec® Stopper & Stelmi RNS 7
  • BD Neopak™ XtraFlow™ 1 mlL Glass Prefillable Syringes 4
  • BD Neopak™ XtraFlow™ 2.25 mL Glass Prefillable Syringe With 8 mm UTW Needle & FluroTec® Stopper & Stelmi RNS 8
Features and Benefits

Improving subcutaneous drug delivery and end-user injection experience1,3

  • Reduce injection force and/or time for a fixed solution viscosity.1,2
    Ejection force or injection time required to push on the plunger rod for viscous solution delivery (10-30Cp) is reduced by up to 57%.*2

Positively impact patient preference3

  • 64% of self-injecting chronic disease patients preferred the BD Neopak™ XtraFlow™ (27G 8mm UTW). Reduced injection force was the main reason given followed by the shorter needle length.3

Reduce intramuscular injection risk by 2.5x to 13x3µ†

Reduce needle-related anxiety3†

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Footnotes

*When compared to 12.7 mm special thin wall needle.

*With BD Neopak™ XtraFlow™ 27G 8 mm ultra-thin wall when compared to the BD Neopak™ 12.7 mm 27G special-thin wall syringe. Ejection force and injection time values were simulated through a mathematical model based on the Hagen-Poiseuille equation

**PFS platform: Serving a range of requirements (silicone reactivity, drug fill volume, viscosity, device integration, etc.) with a minimal number of SKUs and little to no change in core materials (glass, silicone, rubber, etc.)

µ In case of a non-recommended subcutaneous injection technique (45° or 90° angle with no skin pinch) as simulated by mathematical model.

When compared to BD Neopak™ 12.7mm 27G special-thin wall syringe

References

  1. Injection time and ejection force calculation [internal study], Le Pont-de-Claix, France; Becton, Dickinson and Company, 2020
  2. BD Neopak™ XtraFlow™ 2.25 mL prototype evaluation [internal study] , Le Pont-de-Claix, France; Becton, Dickinson, 2020
  3. Pager et al. (2020), “User experience for manual injection of 2 mL viscous solutions is enhanced by a new prefillable syringe with staked 8 mm ultra-thin wall needle”, Expert Opinion on Drug Delivery, https://doi.org/10.1080/17425247.2020.1796630
    * When compared to 12.7 mm special thin wall needle.
  4. BD Medical Pharmaceutical systems_BD Hypak™ Glass Prefillable Syringe since 1975_BD Website.

BD Expertise

BD Expertise in the BD Neopak™ XtraFlow™ Glass Prefillable Syringe

  • BD partnering in combination product development with the biopharmaceutical industry for 30 years.4
  • XtraFlow™ needle technology is built on BD Neopak™ Glass Prefillable Syringe technology
    • Compatible with existing manufacturing and inspection technologies/practices.
    • Supports single PFS platform** approach.

 

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Footnotes

*When compared to 12.7 mm special thin wall needle.

*With BD Neopak™ XtraFlow™ 27G 8 mm ultra-thin wall when compared to the BD Neopak™ 12.7 mm 27G special-thin wall syringe. Ejection force and injection time values were simulated through a mathematical model based on the Hagen-Poiseuille equation

**PFS platform: Serving a range of requirements (silicone reactivity, drug fill volume, viscosity, device integration, etc.) with a minimal number of SKUs and little to no change in core materials (glass, silicone, rubber, etc.)

µ In case of a non-recommended subcutaneous injection technique (45° or 90° angle with no skin pinch) as simulated by mathematical model.

† When compared to BD Neopak™ 12.7mm 27G special-thin wall syringe

References

  1. Injection time and ejection force calculation [internal study], Le Pont-de-Claix, France; Becton, Dickinson and Company, 2020
  2. BD Neopak™ XtraFlow™ 2.25 mL prototype evaluation [internal study] , Le Pont-de-Claix, France; Becton, Dickinson, 2020
  3. Pager et al. (2020), “User experience for manual injection of 2 mL viscous solutions is enhanced by a new prefillable syringe with staked 8 mm ultra-thin wall needle”, Expert Opinion on Drug Delivery, https://doi.org/10.1080/17425247.2020.1796630
    * When compared to 12.7 mm special thin wall needle.
  4. BD Medical Pharmaceutical systems_BD Hypak™ Glass Prefillable Syringe since 1975_BD Website.
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