What Happens During Hemostasis?

• Hemostasis includes the following steps: 
  • Vascular Spasm or Vasoconstriction
    • Vasoconstriction – The narrowing (constriction) of blood vessels by small muscles in their walls. When blood vessels constrict, blood flow is slowed or blocked.⁴
  • Platelet formation
    • Platelet formation – Platelets are produced from very large bone marrow cells called megakaryocytes. As megakaryocytes develop into giant cells, they undergo a process of fragmentation that results in the release of over 1,000 platelets per megakaryocyte.⁵  Platelets contain proteins on their surface that allow them to stick to the injury and to each other.⁶
  • Clot formation/ Blood Coagulation
    • Clot formation/blood coagulation – A platelet plug is formed and the external bleeding stops. Next, small molecules, called clotting factors, cause strands of blood-borne materials, called fibrin, to stick together and seal the inside of the wound. Eventually, the cut blood vessel heals, and the blood clot dissolves after a few days.⁷ 

Why are Hemostatic Agents Needed?

Absorbable hemostatic agents are useful as adjunctive therapy during surgical procedures when conventional methods do not control surgical bleeding.¹

How Do You Use an Absorbable Hemostatic Agent?

• Use of an absorbable hemostatic agent will be dependent upon the form factor of the product and should be used in accordance with the manufacturer’s instructions for use.
• Arista™ AH is a simple to use, absorbable hemostatic powder that is ready to use out of the package and ready to be directly applied to the bleeding site²
• Hemostasis is completed within minutes²

What is Arista ™ AH Absorbable Hemostat?

• Arista™ AH is a 100% plant-based absorbable hemostatic powder derived from purified plant starch.²
• The power of Arista™ AH lies in its Microporous Polysaccharide Hemospheres, a patented blood clotting technology.²

Features and Benefits of Arista™ AH Absorbable Hemostat

Easy to Use: 

• Arista™ AH is ready on-demand with a 5 year shelf life.²
• No mixing and no refrigeration are required.²
• Arista™ AH provides broad area coverage on rough surfaces and in hard-to-reach areas.²

Thrombin-Free and 100% Plant-Based

• Thrombin-free, biocompatible and non-pyrogenic. ²
• Arista™ AH is 100% plant-based. ²

Faster Hemostasis

• Complete Hemostasis is achieved in minutes. ²
• The clotting process begins on contact, regardless of a patient’s coagulation status. ²
• Typically absorbed in 24-48 hours* by amylases. ^2,3

When can Arista™ AH Absorbable Hemostat Be Used?

• Arista™ can be used in a wide variety of surgical procedures (except neurologic and ophthalmic) ²
• It serves as an adjunctive hemostatic device to assist when control of capillary, venous, and arteriolar bleeding by pressure, ligature, and other conventional procedures are ineffective or impractical. ²