Dermal fillers
A portfolio of prefillable syringe solutions to meet your product development and clinician needs within dermal fillers applications.1
- Dermatology
- Addressing Your Needs
Dermal fillers
The use of Hyaluronic Acid
Hyaluronic acid is widely used in dermal fillers applications. It simulates collagen production2 and skin regeneration,2 and has anti-aging2 and moisturizing properties.3
Hyaluronic acid is viscous and exerts a high pressure on the syringe during injection.4 This can impact clinical performance: an international survey found that 45% of dermatologists have experienced leakage (occasionally or relatively often).1
Leakage may lead to undesirable outcomes such as risk of delayed injection and/or underdosing.5*
Delivering dermal fillers
With BD Hylok™ Glass Prefillable Syringe for Hyaluronic Acid
and BD support services
BD HylokTM Glass Prefillable Syringe for Hyaluronic Acid comes with a Luer Lock Adaptor (LLA) to support needle connection.6,7,8
By choosing BD to deliver your hyaluronic acid product you will:
Enjoy support from our teams of experts through all the stages of development, from preclinical and clinical data to launch.
Join 26 of the top 30 pharmaceutical companies who benefit from our 60 years of experience in the industry.
Choose BD to bring your drug to market
BD standardized quality processes and products allow development
flexibility and efficiency, and help speed your hyaluronic acid product
to market.
Explore our products
BD Hylok™ Glass Prefillable Syringe
BD Hylok™ Glass Prefillable Syringe for Hyaluronic acid intradermal, subcutaneous or intraarticular injections
BD Hylok™ Glass Prefillable Syringe
*Based on above stated reference # 1, High leak situation is where a Hyaluronic acid leak is from multiple locations and more than 5 bubbles are observed. High annoyance is where discomfort level is greater than 5 on a severity scale of 10.
- Understand Dermatologists & Rheumatologists perception of HA PFS leakages and the value associated to a leakage/breakage free HA PFS. [Voice of Customer Research, n=170, Regions: US, EU, South Korea, and China]. Pont de Claix, FR: Becton Dickinson and Company; 2018.
- Syed Nasir Abbas Bukhari, et al. Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects - International Journal of Biological Macromolecules - Volume 120, Part B, December 2018, Pages 1682-1695
- Anca Maria Juncan, et al. Advantages of Hyaluronic Acid and Its Combination with Other Bioactive Ingredients in Cosmeceuticals - Molecules. 2021 Aug; 26(15): 4429.PMCID: PMC8347214 - PMID: 34361586
- Monheit, G. D., & Coleman, K. M. (2006). Hyaluronic acid fillers. Dermatologic therapy, 19(3), 141-150.
- Voice of Customer research, The MarketTech Group. February 2018. N =170 dermatologists, rheumatologists and orthopedic surgeons (US, EU, Asia)
- BD Hylok™ Design verification results [Internal Report]. Pont-de-Claix, Becton Dickinson and Company, 2016.
- BD Hylok Human Factors study (Executive Summary) - Pont-de-Claix, FR: Becton Dickinson and Company; 2017. The human factors study was a monocentric, single session, randomized, simulated validation study conducted in July 2017 in New York City and Boston by FarmDesign Inc. The study included Nurses= 15 and Dermatologists= 15 for conducting Intra-articular and Intradermal Hyaluronic Acid injections. 'For trained intended users as defined in the Human Factors evaluation.
- BD Hylok™ IV connectors and needles compatibility [Internal Report]. Pont-de-Claix, Becton Dickinson and Company, 2016