System Performance
Choose BD as your partner for combination product development, and benefit from our deep knowledge of injection science, device technology and drug delivery systems
- The Global Market and Growing Burden on Pharma
- System Performance for Quality and Experience
- One Supplier, integrating many components
Combination Product Development
A long and complicated process
Our global population is rapidly aging and the need for biological therapies to treat chronic disease continues to rise, trending towards home care and self-injection.1
Developing an injectable combination product to meet these healthcare demands requires expertise in components, system integration and manufacturing.
When bringing your combination product to market, the drug delivery system you choose must address some or all of the following:
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Deliver your drug safely and effectively efficiently throughout its entire life cycle.
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Support choice and flexibility to serve diverse patient groups, therapeutic areas and markets.
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Demonstrate safe and effective use through Human Factors testing.
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Integrate with a broad range of secondary delivery systems.
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Satisfy your budget and accessibility requirements.
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Perform consistently over millions of units.
With reliable BD system performance, we can help de-risk your product development and help prevent costs due to schedule delays.
Drug Delivery Systems Integration
Backed by Experience and Data
Partner with BD to benefit from our industry-wide expertise
and advanced technology
Developing a drug delivery system with separate components can be difficult. Risks include inconsistent system performance and incompatibility of container components.
Some real challenges faced with non-integrated prefillable syringe (PFS) components are:
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Unreliable removal of the rigid needle shield
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Injection issues arising from uncapping problems
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An injection that does not start, is slow or incomplete
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High injection time and depth variability
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Prefillable syringe breakage during injection or during drop testing
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Prefillable syringe breakage and high reject rate during assembly
These risks bring increased project management complexity, delays and costs
With billions of primary containers and secondary devices manufactured, BD can also support solutions tailored to your combination product development program.
Our integrated, patient-centric drug delivery systems feature:
BD comprehensive systems engineering and integrated
approaches are applied to ensure that each component
function cohesively and reliably.
BD also provides:
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Supportive system-level data to anticipate and retire risk, early in development
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Accurate data for combination product registration across all our components
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Worldwide expertise in regulatory and technical documentation
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Design control in Human Factors, Usability, and clinical evaluation.
Partner with BD to mitigate risks to your
combination product development and ease the
path to market approval, getting your final drug
product to patients as soon as possible.
Effective System Integration Streamlines Combination Product Development
BD Approaches to System Integration: Enabling System Integration
Working with multiple suppliers can be time-consuming, and you must act as the Systems Integrator.
How do you avoid the problems that can arise from working with multiple suppliers and with systems that are not fully integrated?
The answer is simple: work with BD as your single supplier as a trusted partner.
To support the development of your drug delivery system, our cross functional team of technical, development, regulatory affairs, quality and medical experts offer advice on:
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Optimal combination of subsystems
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Regulation of combination products
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Minimization of manufacturing risk
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Supply chain efficiency
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Traceability
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Lifecycle management
Make BD your partner of choice for end-to-end combination
Explore our products
Prefillable syringe systems
BD is uniquely positioned to offer prefillable syringe systems with expertise in drug container interactions, primary container selection and container/device integration for various drug therapies.
Safety and shielding systems
BD offers a wide range of safety and shielding systems that feature innovative needle shielding system technology for your injectable drug.
Self injection systems
BD partners with you to develop self injection systems that enable drug administration across a range of volumes and viscosities, leveraging BD primary container technologies and expertise with a focus on reaching the market faster.
Plunger Stoppers
With our two stopper processing sites, we aim to offer security of supply and business continuity for your drug combination product needs.
Backstops and plunger rods
As part of our integrated approach to help you develop drug combination products, we offer BD Backstops and BD Plunger Rods in a range of sizes, materials and colors.
Autoplay:
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Prefillable syringe systems
Safety and shielding systems
Self injection systems
Plunger Stoppers
Backstops and plunger rods
*BD Libertas is a product in development; some statements are forward looking and subject to a variety of risks and uncertainties
- Landers S, Madigan E, Leff B, et al. The Future of Home Health Care: A Strategic Framework for Optimizing Value. Home Health Care Manag Pract. 2016;28(4):262 278. doi:10.1177/1084822316666368 - REF-840